Ad5CMVIkappaBalpha(Y42F)

Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of IkappaBalpha(mutant Y42F). The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Fan, C., Li, Q., Zhang, Y., Liu, X., Luo, M., Abbott, D., Zhou, W., and Engelhardt, J.F. 2004. IkappaBalpha and IkappaBbeta possess injury context-specific functions that uniquely influence hepatic NF-kappaB induction and inflammation. J Clin Invest 113:746-755.