Ad5CMVIKKbeta(K/M)

Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of IKKbeta(dominant negative mutant K44M). The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Sanlioglu, S., C. M. Williams, et al. (2001). "Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B." J Biol Chem 276(32): 30188-98.